1-Iodo-4-(trifluoromethoxy)benzene(CAS#103962-05-6)
| Hazard Symbols | Xi – Irritant |
| Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29093090 |
| Hazard Class | IRRITANT |
Introduction
Trifluoromethoxyiodobenzene is an organic compound with the chemical formula C7H4F3IO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in organic solvents such as chloroform and ether
-Melting point: about 30-32 degrees Celsius
-Boiling point: about 270-271 degrees Celsius
Use:
Trifluoromethoxyiodobenzene has important application value in organic synthesis and can be used as a fluorination reagent and catalyst for aromatic compounds. It is mainly used in the fluorination reaction of aromatic hydrocarbons in organic synthesis, and has the characteristics of high efficiency, selectivity and mildness. In addition, it can also be used in organic synthesis of esterification, thioetherification, hydroxyl alcohol etherification and other reactions.
Preparation Method:
The preparation method of trifluoromethoxyiodobenzene is relatively simple. A common preparation method is to add trifluoroformate or lithium trifluoroformate to an ethereal solution of iodobenzene and react by slow heating. The reaction is usually carried out under an inert atmosphere to avoid the influence of oxygen on the reaction.
Safety Information:
trifluoromethoxy iodobenzene is an organic compound. Attention should be paid to its irritation to eyes, skin and mucous membranes during operation. Suitable personal protective equipment, such as lab gloves and protective glasses, should be worn during operation or contact. Due to its toxicity and irritation, it should be used under well-ventilated laboratory conditions and avoid inhalation or ingestion of this compound. In case of inadvertent contact or ingestion, seek medical attention immediately.
