(1-Hexadecyl)triphenylphosphonium bromide (CAS# 14866-43-4)
(1-Hexadecyl) triphenylphosphine bromide is an organic compound. Here is an introduction to its properties, uses, manufacturing methods, and safety information:
nature:
(1-Hexadecyl) triphenylphosphine bromide is a colorless crystalline solid with a strong odor. At room temperature, it is insoluble in water, but soluble in organic solvents such as ether and benzene.
Purpose:
(1-Hexadecyl) triphenylphosphine bromide is mainly used as a catalyst in organic synthesis. It can be used as an alkylating agent, hydrogenating agent, aminating agent, etc. It is also commonly used in the synthesis of heterocyclic compounds, spirocyclic compounds, and organic molecules with biological activity. Due to its electron unsaturation property, it can also be used as a fluorescent probe and chemical sensor.
Manufacturing method:
The preparation method of (1-hexadecyl) triphenylphosphine bromide is relatively complex, usually using phosphorus bromide (PBr3) and phenyl magnesium halide (PhMgBr) as raw materials. Reacting the two yields the intermediate (1-hexadecyl) triphenylphosphine bromide magnesium (Ph3PMgBr). The target product can be obtained by hydrolysis or reaction with other compounds.
Security information:
(1-Hexadecyl) triphenylphosphine bromide has certain toxicity and irritation, and should be used and stored in accordance with the safety operating procedures of chemicals. Avoid contact with skin, eyes, and respiratory tract. The workplace should maintain good ventilation and be equipped with personal protective equipment such as gloves, safety goggles, and face shields.