1 3-Bis(trifluoromethyl)benzene（CAS# 402-31-3)
| Risk Codes | R10 – Flammable R36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S24/25 – Avoid contact with skin and eyes. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| TSCA | T |
| HS Code | 29039990 |
| Hazard Note | Flammable |
| Hazard Class | 3 |
| Packing Group | III |
Introduction
1,3-Bis(trifluoromethyl)benzene is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of this compound:
Quality:
- Appearance: Colorless liquid or solid.
- Solubility: Soluble in organic solvents, almost insoluble in water.
- Toxicity: It has some toxicity.
Use:
1,3-Bis(trifluoromethyl)benzene has important applications in organic synthesis:
- As a reagent: used in trifluoromethylation reactions in organic synthesis reactions.
Method:
There are two main preparation methods for 1,3-bis(trifluoromethyl)benzene:
- Fluorination reaction: 1,3-bis(trifluoromethyl)benzene is obtained by the reaction of benzene and trifluoromethane catalyzed by chromium chloride (CrCl3).
- Iodization reaction: 1,3-bis(trifluoromethyl)benzene is prepared by reacting with trifluoromethane in the presence of iron iodide (FeI2) by 1,3-bis(iodomethyl)benzene.
Safety Information:
1,3-Bis(trifluoromethyl)benzene is an organic compound, and the following safety precautions should be paid attention to when using it:
- Toxicity: The compound has some toxicity and should be avoided from contact with the skin, inhalation, or ingestion.
- Fire risk: 1,3-bis(trifluoromethyl)benzene is a flammable substance and should be kept away from open flames and high temperatures, and stored in a cool, well-ventilated place.
- Personal protection: Appropriate protective gloves, glasses and protective clothing should be worn during use.
- Waste disposal: When disposing of waste, appropriate measures should be taken for recycling, treatment or safe disposal to avoid pollution to the environment.
